GHK-Cu reconstitution calculator

GHK-Cu at a glance

50mg vial + 2.5mL BAC water = 5 units = 1mg — Frequency: 5 days/week (e.g. weekdays) — Best taken: any consistent time, injection sites commonly rotated

Full GHK-Cu dosing reference — reconstitution per vial size, dose-to-units table, side effects and sources.

What it does

• Naturally occurring copper-binding peptide found in human plasma, saliva, and urine that declines with age.
• Well-studied topically and in lab settings for boosting collagen production and skin repair.
• Also studied for supporting hair follicle activity and general wound healing.
• FDA materials flag compounded injectable GHK-Cu specifically as a safety concern — topical use is more established.
• A 2018 review (co-authored by GHK-Cu's discoverer, who also sells copper-peptide skincare) proposes anti-cancer mechanisms — stimulating DNA-repair genes, reducing inflammation, and blocking oxidative damage linked to cancer risk. Evidence is animal/cell-culture and gene-expression data, not a human cancer-incidence trial.

GHK-Cu binds copper very tightly. Copper-chelating medications (penicillamine, trientine — used for Wilson's disease) work directly against it, and combining the two can produce unpredictable copper levels for both the drug and the peptide. Anyone with a copper-metabolism disorder should avoid GHK-Cu.

Notes

Listed titration schedule: 1.0mg (5 units) → 1.5mg (7.5 units) → 2.0mg (10 units), 5 days/week. FDA materials flag compounded injectable GHK-Cu as a safety concern due to limited human safety data. The 50mg reference vial mixes to 20mg/mL. Larger vial size options are capped at ~3mL BAC water instead of diluted further, so they come out more concentrated (fewer units per dose) than this reference size.

Side Effects

• Mild, short-lived redness or itching at the site.
• Rare allergic reactions with copper sensitivity.
• Topical use is well documented; injectable use far less so.
• Copper load matters in copper-metabolism conditions (Wilson's disease).

GHK-Cu vial sizes and concentrations

Standard water for each GHK-Cu vial size in the Dosify Me data, and the concentration it gives. One unit is 0.01 mL on a U-100 insulin syringe.

^* This size is conventionally mixed more concentrated rather than diluted further — fewer units per dose than smaller vials of this peptide.

Syringe units for the listed quantities, by vial size

Worked example for GHK-Cu

1. The example vial: 100 mg of GHK-Cu, mixed with 3.00 mL of bacteriostatic water.
2. Concentration: 100 mg ÷ 3.00 mL = 33.33 mg/mL.
3. One syringe unit is 0.01 mL, so it holds 33.33 mg/mL × 0.01 mL = 0.333 mg (333.33 mcg).
4. Example quantity: 1000 mcg = 1 mg.
5. Volume: 1 mg ÷ 33.33 mg/mL = 0.03 mL.
6. Syringe reading: 0.03 mL × 100 = 3 units.

Label numbers from the Dosify Me data, used to show the arithmetic. Not a recommendation of any quantity.

Frequently asked

How many units is 1 mg of GHK-Cu?

At 20 mg/mL (the standard mix for vials up to 50 mg), 1 mg of GHK-Cu is 5.0 units on a 100-unit insulin syringe (0.050 mL).

How many units is 1.5 mg of GHK-Cu?

At 20 mg/mL (the standard mix for vials up to 50 mg), 1.5 mg of GHK-Cu is 7.5 units on a 100-unit insulin syringe (0.075 mL).

How many units is 2 mg of GHK-Cu?

At 20 mg/mL (the standard mix for vials up to 50 mg), 2 mg of GHK-Cu is 10.0 units on a 100-unit insulin syringe (0.100 mL).

How much bacteriostatic water do I add to a 50 mg vial of GHK-Cu?

2.50 mL, which gives 20 mg/mL. Larger vials hold at most 3 mL of water, so they are mixed more concentrated and need fewer units per dose.

How much bacteriostatic water do I add to a 100 mg vial of GHK-Cu?

3.00 mL, which gives 33.33 mg/mL. This size holds at most 3 mL of water, so it is mixed more concentrated and the same dose is fewer units than from a smaller vial.

How often is GHK-Cu taken?

5 days/week. Any consistent time, injection sites commonly rotated Typical cycle: 4 weeks on, ~1–2 weeks off; repeat 2–3×/year.

Related pages and guides

• GHK-Cu dosing reference
• How many units is 250 mcg?
• How much bacteriostatic water for a 5 mg vial?
• U-100 vs U-50 insulin syringe for peptides
• Peptide injection site rotation
• All peptide guides

Other calculators

General peptide calculator · BAC water calculator · Peptide dosing chart · How to reconstitute peptides · mcg to units chart