Semax reconstitution calculator

Semax at a glance

10mg vial + 2mL BAC water = 6 units = 300mcg — Frequency: daily, 10-day cycles — Best taken: mornings

Full Semax dosing reference — reconstitution per vial size, dose-to-units table, side effects and sources.

What it does

• Synthetic fragment derived from ACTH, modified for stability without raising cortisol.
• Studied for cognitive effects — improved attention and short-term memory in small human studies.
• Proposed mechanism includes boosting BDNF/NGF (brain growth factors) and reducing inflammation after injury.
• Approved in Russia for cognitive support and post-stroke neuroprotection; not FDA-approved.

No study, case report or label describes Semax combined with an MAOI. The concern rests on mechanism — Semax is reported to affect brain monoamine signaling, and MAOIs block the breakdown of those same monoamines — so it is an untested combination with a plausible reason for caution, not a documented danger. Overlap with SSRIs/SNRIs is the same kind of unstudied concern. Talk to your prescribing doctor before combining with any antidepressant.

Notes

No single consensus protocol — community subcutaneous protocols are reported at 300-1000mcg once daily, titrated gradually. All vial sizes reconstitute to 5mg/mL (50mcg/unit) so the syringe reads the same regardless of size.

Side Effects

• Nasal irritation or congestion with spray use.
• Transient headache, worse if dehydrated.
• Irritability, sleep or appetite changes; insomnia if dosed late.
• Mild fatigue early; slight heart-rate rise in some.

Semax vial sizes and concentrations

Standard water for each Semax vial size in the Dosify Me data, and the concentration it gives. One unit is 0.01 mL on a U-100 insulin syringe.

Syringe units for the listed quantities, by vial size

Worked example for Semax

1. The example vial: 10 mg of Semax, mixed with 2.00 mL of bacteriostatic water.
2. Concentration: 10 mg ÷ 2.00 mL = 5 mg/mL.
3. One syringe unit is 0.01 mL, so it holds 5 mg/mL × 0.01 mL = 0.05 mg (50 mcg).
4. Example quantity: 300 mcg = 0.3 mg.
5. Volume: 0.3 mg ÷ 5 mg/mL = 0.06 mL.
6. Syringe reading: 0.06 mL × 100 = 6 units.

Label numbers from the Dosify Me data, used to show the arithmetic. Not a recommendation of any quantity.

Frequently asked

How many units is 300 mcg of Semax?

At 5 mg/mL (the concentration every vial size mixes to), 300 mcg of Semax is 6.0 units on a 100-unit insulin syringe (0.060 mL).

How many units is 500 mcg of Semax?

At 5 mg/mL (the concentration every vial size mixes to), 500 mcg of Semax is 10.0 units on a 100-unit insulin syringe (0.100 mL).

How many units is 800 mcg of Semax?

At 5 mg/mL (the concentration every vial size mixes to), 800 mcg of Semax is 16.0 units on a 100-unit insulin syringe (0.160 mL).

How much bacteriostatic water do I add to a 5 mg vial of Semax?

1.00 mL, which gives 5 mg/mL. Other vial sizes use proportionally more or less water so the syringe reads the same.

How much bacteriostatic water do I add to a 10 mg vial of Semax?

2.00 mL, which gives 5 mg/mL. Other vial sizes use proportionally more or less water so the syringe reads the same.

How often is Semax taken?

Daily, 10-day cycles. Mornings, any consistent time Typical cycle: ~10 days on, ~1 week off; repeat as needed.

Related pages and guides

• Semax dosing reference
• How many units is 250 mcg?
• How much bacteriostatic water for a 5 mg vial?
• U-100 vs U-50 insulin syringe for peptides
• How to track peptide doses
• All peptide guides

Other calculators

General peptide calculator · BAC water calculator · Peptide dosing chart · How to reconstitute peptides · mcg to units chart