Survodutide reconstitution calculator

Survodutide at a glance

10mg vial + 2mL BAC water = 6 units = 300mcg — Frequency: weekly — Best taken: same day each week

Full Survodutide dosing reference — reconstitution per vial size, dose-to-units table, side effects and sources.

What it does

• A GLP-1/glucagon dual receptor agonist, in the same class as mazdutide, developed for obesity and liver disease (MASH).
• The GLP-1 side acts on appetite-regulating brain regions to reduce how much food the brain wants to take in, while also slowing gastric emptying to extend fullness after meals.
• The glucagon side acts mainly on the liver, increasing energy expenditure and helping mobilize and burn stored fat — this dual action is what drives its added benefit for liver fat (MASH) on top of weight loss.
• Late-stage clinical trials show significant weight loss and improvements in liver fat.
• Not yet independently FDA-approved — still in clinical development as of this writing.

Its GLP-1 activity slows digestion, which can change absorption of other oral medications, including thyroid medication. Combined with insulin or a sulfonylurea, the added blood-sugar-lowering effect can cause hypoglycemia — those doses often need to be reduced first. Talk to your prescribing doctor before combining.

Notes

All vial sizes reconstitute to 5mg/mL (50mcg/unit) so the syringe reads the same regardless of size.

Side Effects

• Nausea, vomiting, diarrhea, constipation — usually mild and transient.
• Modest resting heart rate increase.
• Still in Phase 3; real-world data limited.

Survodutide strength and syringe units

Survodutide ships ready to use, so no water is added. The strength is 5 mg/mL, so one syringe unit (0.01 mL on a U-100 insulin syringe) holds 0.05 mg.

Worked example for Survodutide

1. Strength: 5 mg/mL, ready to use.
2. Example quantity: 300 mcg = 0.3 mg.
3. Volume: 0.3 mg ÷ 5 mg/mL = 0.06 mL.
4. Syringe reading: 0.06 mL × 100 = 6 units.

Label numbers from the Dosify Me data, used to show the arithmetic. Not a recommendation of any quantity.

Frequently asked

How many units is 300 mcg of Survodutide?

At 5 mg/mL (the concentration every vial size mixes to), 300 mcg of Survodutide is 6.0 units on a 100-unit insulin syringe (0.060 mL).

How many units is 600 mcg of Survodutide?

At 5 mg/mL (the concentration every vial size mixes to), 600 mcg of Survodutide is 12.0 units on a 100-unit insulin syringe (0.120 mL).

How many units is 1.2 mg of Survodutide?

At 5 mg/mL (the concentration every vial size mixes to), 1.2 mg of Survodutide is 24.0 units on a 100-unit insulin syringe (0.240 mL).

How much bacteriostatic water do I add to a 10 mg vial of Survodutide?

2.00 mL, which gives 5 mg/mL. This compound ships pre-mixed, so no water is added.

How often is Survodutide taken?

Weekly. Same day each week, any time Typical cycle: Often run continuously; tapering is done under guidance.

Related pages and guides

• Survodutide dosing reference
• How many units is 250 mcg?
• U-100 vs U-50 insulin syringe for peptides
• How to track peptide doses
• All peptide guides

Other calculators

General peptide calculator · BAC water calculator · Peptide dosing chart · How to reconstitute peptides · mcg to units chart