Tesamorelin reconstitution calculator

Tesamorelin at a glance

5mg vial + 1.25mL BAC water = 35 units = 1.4mg — Frequency: daily — Best taken: bedtime, ≥90 min before eating (empty stomach)

Full Tesamorelin dosing reference — reconstitution per vial size, dose-to-units table, side effects and sources.

What it does

• Growth hormone-releasing hormone (GHRH) analog that stimulates the pituitary to release growth hormone.
• FDA-approved (as Egrifta SV) specifically for reducing excess abdominal fat in HIV-associated lipodystrophy.
• Clinical trials show measurable reduction in visceral (deep abdominal) fat with continued use.
• Effects diminish after stopping — visceral fat tends to return within months of discontinuation.

The FDA label warns tesamorelin can raise blood sugar and may unmask or worsen diabetes, working against insulin and other diabetes medications. Raising growth hormone can also unmask previously hidden hypothyroidism and shift how the body converts thyroid hormone, so anyone on thyroid medication should have levels monitored (especially in the first 6 months). Talk to your prescribing doctor before combining.

Notes

FDA-approved (as Egrifta SV) for HIV-associated lipodystrophy at this exact dose — the current label mixes to 4mg/mL (a 2mg single-dose vial + 0.5mL diluent) and delivers 1.4mg in 35 units. Injection sites are rotated to reduce lipoatrophy risk. The 5mg and 10mg compounded-vial options here also mix to that same 4mg/mL; the 20mg option is capped at 3mL BAC water instead, so it comes out more concentrated (fewer units per dose). The FDA-approved label uses continuous daily dosing with no scheduled break. Separately, off-label wellness-community protocols commonly cycle it — roughly 60-90 days on, then about 30 days off — to reduce pituitary receptor desensitization. This app defaults to daily to match the approved label.

Side Effects

• Injection site redness, itching, or swelling.
• Fluid retention in hands or feet; joint or muscle pain.
• Can raise blood sugar or unmask diabetes.
• Not for critically ill patients — GH-stimulating drugs linked to higher mortality there.

Tesamorelin vial sizes and concentrations

Standard water for each Tesamorelin vial size in the Dosify Me data, and the concentration it gives. One unit is 0.01 mL on a U-100 insulin syringe.

^* This size is conventionally mixed more concentrated rather than diluted further — fewer units per dose than smaller vials of this peptide.

Worked example for Tesamorelin

1. The example vial: 20 mg of Tesamorelin, mixed with 3.00 mL of bacteriostatic water.
2. Concentration: 20 mg ÷ 3.00 mL = 6.67 mg/mL.
3. One syringe unit is 0.01 mL, so it holds 6.67 mg/mL × 0.01 mL = 0.067 mg (66.67 mcg).
4. Example quantity: 1400 mcg = 1.4 mg.
5. Volume: 1.4 mg ÷ 6.67 mg/mL = 0.21 mL.
6. Syringe reading: 0.21 mL × 100 = 21 units.

Label numbers from the Dosify Me data, used to show the arithmetic. Not a recommendation of any quantity.

Frequently asked

How many units is 1.4 mg of Tesamorelin?

At 4 mg/mL (the standard mix for vials up to 10 mg), 1.4 mg of Tesamorelin is 35.0 units on a 100-unit insulin syringe (0.350 mL).

How much bacteriostatic water do I add to a 5 mg vial of Tesamorelin?

1.25 mL, which gives 4 mg/mL. Larger vials hold at most 3 mL of water, so they are mixed more concentrated and need fewer units per dose.

How much bacteriostatic water do I add to a 10 mg vial of Tesamorelin?

2.50 mL, which gives 4 mg/mL. Larger vials hold at most 3 mL of water, so they are mixed more concentrated and need fewer units per dose.

How much bacteriostatic water do I add to a 20 mg vial of Tesamorelin?

3.00 mL, which gives 6.67 mg/mL. This size holds at most 3 mL of water, so it is mixed more concentrated and the same dose is fewer units than from a smaller vial.

How often is Tesamorelin taken?

Daily. Bedtime, ≥90 min before eating (empty stomach) Typical cycle: 12–16 weeks on, ~4 weeks off; repeat 1–2×/year.

Related pages and guides

• Tesamorelin dosing reference
• How many units is 250 mcg?
• How much bacteriostatic water for a 5 mg vial?
• U-100 vs U-50 insulin syringe for peptides
• Peptide injection site rotation
• All peptide guides

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General peptide calculator · BAC water calculator · Peptide dosing chart · How to reconstitute peptides · mcg to units chart