Melanotan II reconstitution calculator

Melanotan II at a glance

10mg vial + 2mL BAC water = 5 units = 250mcg — Frequency: daily loading, then 2-3x weekly — Best taken: before sun exposure

Full Melanotan II dosing reference — reconstitution per vial size, dose-to-units table, side effects and sources.

What it does

• A stronger, less selective melanocortin agonist than Melanotan I — also studied for libido (it is the basis of the approved drug Vyleesi) and appetite suppression.
• Produces a faster, deeper tan than Melanotan I, but with a notably higher rate of nausea, flushing, and spontaneous erections/libido effects.
• Not approved for cosmetic tanning use — significant, well-documented side-effect profile compared to most other entries in this list.

Melanocortin agonism acutely raises blood pressure and heart rate. Anyone on blood pressure medication (beta-blockers, ACE inhibitors, calcium channel blockers) should use caution, and uncontrolled hypertension or significant cardiovascular disease is a reason to avoid this peptide. Talk to your doctor first.

Notes

All vial sizes reconstitute to 5mg/mL (50mcg/unit) so the syringe reads the same regardless of size.

Side Effects

• Nausea in ~30-65%, especially early doses.
• Flushing, fatigue, yawning in the first hour.
• Spontaneous erections in men 1-5 hours after dosing.
• Darkening moles — theoretical melanoma risk; get changing moles checked.

Melanotan II vial sizes and concentrations

Standard water for each Melanotan II vial size in the Dosify Me data, and the concentration it gives. One unit is 0.01 mL on a U-100 insulin syringe.

Worked example for Melanotan II

1. The example vial: 10 mg of Melanotan II, mixed with 2.00 mL of bacteriostatic water.
2. Concentration: 10 mg ÷ 2.00 mL = 5 mg/mL.
3. One syringe unit is 0.01 mL, so it holds 5 mg/mL × 0.01 mL = 0.05 mg (50 mcg).
4. Example quantity: 250 mcg = 0.25 mg.
5. Volume: 0.25 mg ÷ 5 mg/mL = 0.05 mL.
6. Syringe reading: 0.05 mL × 100 = 5 units.

Label numbers from the Dosify Me data, used to show the arithmetic. Not a recommendation of any quantity.

Frequently asked

How many units is 250 mcg of Melanotan II?

At 5 mg/mL (the concentration every vial size mixes to), 250 mcg of Melanotan II is 5.0 units on a 100-unit insulin syringe (0.050 mL).

How many units is 500 mcg of Melanotan II?

At 5 mg/mL (the concentration every vial size mixes to), 500 mcg of Melanotan II is 10.0 units on a 100-unit insulin syringe (0.100 mL).

How many units is 1 mg of Melanotan II?

At 5 mg/mL (the concentration every vial size mixes to), 1 mg of Melanotan II is 20.0 units on a 100-unit insulin syringe (0.200 mL).

How much bacteriostatic water do I add to a 10 mg vial of Melanotan II?

2.00 mL, which gives 5 mg/mL. Other vial sizes use proportionally more or less water so the syringe reads the same.

How often is Melanotan II taken?

Daily during loading, then 2-3x weekly. Before sun exposure Typical cycle: Loading, then 2–3×/week to maintain; pause when tan is reached.

Related pages and guides

• Melanotan II dosing reference
• How many units is 250 mcg?
• How much bacteriostatic water for a 5 mg vial?
• U-100 vs U-50 insulin syringe for peptides
• How to track peptide doses
• All peptide guides

Other calculators

General peptide calculator · BAC water calculator · Peptide dosing chart · How to reconstitute peptides · mcg to units chart