Also known as Afamelanotide
Anti-Aging & Skin
10mg vial + 2mL BAC water = 5 units = 250mcg — Amounts listed in the Dosify Me data: 250mcg-1mg — Frequency: daily loading, then 2-3x weekly — Best taken: before sun exposure
Informational only, not medical advice. Consult a licensed healthcare provider before starting or changing any protocol.
Amounts and schedules here are listed from the Dosify Me compound data (sources below). They are not recommendations: Dosify Me does not tell you what dose to take, so follow your prescriber.
Every vial size below is mixed to the same concentration, 5 mg/mL, so the syringe reads the same number of units for a given dose no matter which vial you bought.
| Vial | Bacteriostatic water | Concentration |
|---|---|---|
| 10 mg | 2.00 mL | 5 mg/mL |
On a standard 100-unit (1 mL) insulin syringe, at the concentration above:
| Dose | Syringe units |
|---|---|
| 250 mcg | 5.0 units |
| 500 mcg | 10.0 units |
| 1 mg | 20.0 units |
Amounts listed in the Dosify Me data: 250–1000 mcg. Frequency: daily during loading, then 2-3x weekly. Timing: before sun exposure.
All vial sizes reconstitute to 5mg/mL (50mcg/unit) so the syringe reads the same regardless of size.
Check one row of the table above: 250 mcg is 0.25 mg; 0.25 mg ÷ 5 mg/mL = 0.05 mL; 0.05 mL × 100 = 5 units.
Anecdotal and early-research reports, kept apart from the evidence above. Not clinically established.
Blood pressure and heart rate effects are widely claimed for Melanotan I but are not documented for its approved equivalent afamelanotide, which is selective for the skin-pigment receptor and whose label lists no such adverse reactions and no interaction studies. Those cardiovascular effects belong to non-selective melanocortin agonists like bremelanotide. Anyone on blood pressure medication (beta-blockers, ACE inhibitors, calcium channel blockers) should still mention it to their prescribing doctor and watch their numbers.
Different vial or dose? Open the Melanotan I reconstitution calculator, pre-filled with these numbers.
At 5 mg/mL (the concentration every vial size mixes to), 250 mcg of Melanotan I is 5.0 units on a 100-unit insulin syringe (0.050 mL).
At 5 mg/mL (the concentration every vial size mixes to), 500 mcg of Melanotan I is 10.0 units on a 100-unit insulin syringe (0.100 mL).
At 5 mg/mL (the concentration every vial size mixes to), 1 mg of Melanotan I is 20.0 units on a 100-unit insulin syringe (0.200 mL).
2.00 mL, which gives 5 mg/mL. Other vial sizes use proportionally more or less water so the syringe reads the same.
Daily during loading, then 2-3x weekly. Before sun exposure Typical cycle: Loading, then 2–3×/week to maintain; pause when tan is reached.
Dosify Me does this math for you. Pick the compound, your vial size and dose, and the app draws the exact syringe reading, keeps your schedule and reminders, and logs every dose — privately, on your phone.
Published by San Tan Group, LLC, the company that makes the Dosify Me app. About Dosify Me
Figures come from the Dosify Me compound database for Melanotan I: concentration is the vial amount ÷ the water volume, and syringe units are the volume in mL × 100 on a U-100 syringe.
Last checked: (changes only when the Melanotan I data changes)
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Figures generated from the Dosify Me compound database on 2026-10-15. Informational use only — not medical advice.