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Semaglutide

Weight Loss & Metabolic Heart Health Diabetes

10mg vial + 2mL BAC water = 5 units = 250mcg — Amounts listed in the Dosify Me data: 250mcg-2.4mg, titrated up over ~17 weeks — Frequency: weekly — Best taken: same day each week, any time

Informational only, not medical advice. Consult a licensed healthcare provider before starting or changing any protocol.

Amounts and schedules here are listed from the Dosify Me compound data (sources below). They are not recommendations: Dosify Me does not tell you what dose to take, so follow your prescriber.

Reconstitution

Vial sizes up to 10 mg are mixed to 5 mg/mL. Larger vials hold at most 3 mL of water, so they are mixed more concentrated and need fewer units per dose.

VialBacteriostatic waterConcentration
5 mg1.00 mL5 mg/mL
10 mg2.00 mL5 mg/mL
20 mg*3.00 mL6.67 mg/mL

* This size is conventionally mixed more concentrated rather than diluted further — fewer units per dose than smaller vials of this peptide.

Dose to syringe units

On a standard 100-unit (1 mL) insulin syringe, for vials mixed to 5 mg/mL (sizes marked * are more concentrated and need fewer units):

DoseSyringe units
250 mcg5.0 units
500 mcg10.0 units
1 mg20.0 units
1.7 mg34.0 units
2.4 mg48.0 units

Amounts listed in the Dosify Me data: 250–2400 mcg. Frequency: weekly. Timing: same day each week, any time of day.

Listed titration schedule: weeks 1-4 250mcg, weeks 5-8 500mcg, weeks 9-12 1000mcg, weeks 13-16 1700mcg, weeks 17+ 2400mcg (maintenance). The 10mg reference vial mixes to 5mg/mL. Larger vial size options are capped at ~3mL BAC water instead of diluted further, so they come out more concentrated (fewer units per dose) than this reference size.

Reading units for Semaglutide

Check one row of the table above: 250 mcg is 0.25 mg; 0.25 mg ÷ 5 mg/mL = 0.05 mL; 0.05 mL × 100 = 5 units.

What it does

Why it is listed under Weight Loss & Metabolic, Heart Health, Diabetes

What users report

Anecdotal and early-research reports, kept apart from the evidence above. Not clinically established.

Side effects

Medication caution

Slows gastric emptying, which changes how other oral medications are absorbed. The roughly one-third rise in thyroid medication (levothyroxine) exposure comes from the oral semaglutide tablet label, where the tablet's absorption enhancer is part of the mechanism — the injectable label carries no levothyroxine data at all. Combined with insulin or a sulfonylurea, the added blood-sugar-lowering effect can cause hypoglycemia — those doses often need to be reduced first. Talk to your prescribing doctor before combining.

Commonly paired with

Semaglutide calculator

Different vial or dose? Open the Semaglutide reconstitution calculator, pre-filled with these numbers.

Frequently asked

How many units is 250 mcg of Semaglutide?

At 5 mg/mL (the standard mix for vials up to 10 mg), 250 mcg of Semaglutide is 5.0 units on a 100-unit insulin syringe (0.050 mL).

How many units is 500 mcg of Semaglutide?

At 5 mg/mL (the standard mix for vials up to 10 mg), 500 mcg of Semaglutide is 10.0 units on a 100-unit insulin syringe (0.100 mL).

How many units is 1 mg of Semaglutide?

At 5 mg/mL (the standard mix for vials up to 10 mg), 1 mg of Semaglutide is 20.0 units on a 100-unit insulin syringe (0.200 mL).

How much bacteriostatic water do I add to a 5 mg vial of Semaglutide?

1.00 mL, which gives 5 mg/mL. Larger vials hold at most 3 mL of water, so they are mixed more concentrated and need fewer units per dose.

How much bacteriostatic water do I add to a 10 mg vial of Semaglutide?

2.00 mL, which gives 5 mg/mL. Larger vials hold at most 3 mL of water, so they are mixed more concentrated and need fewer units per dose.

How much bacteriostatic water do I add to a 20 mg vial of Semaglutide?

3.00 mL, which gives 6.67 mg/mL. This size holds at most 3 mL of water, so it is mixed more concentrated and the same dose is fewer units than from a smaller vial.

How often is Semaglutide taken?

Weekly. Same day each week, any time of day Typical cycle: Often run continuously; tapering is done under guidance.

Is “sema” the same as Semaglutide?

Yes. “sema” is the short name people use for Semaglutide in forums and search, and every figure on this page is for that same compound. The units, water and schedule above do not change with the spelling.

Dosify Me does this math for you. Pick the compound, your vial size and dose, and the app draws the exact syringe reading, keeps your schedule and reminders, and logs every dose — privately, on your phone.

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Sources

About these figures

Published by San Tan Group, LLC, the company that makes the Dosify Me app. About Dosify Me

Figures come from the Dosify Me compound database for Semaglutide: concentration is the vial amount ÷ the water volume, and syringe units are the volume in mL × 100 on a U-100 syringe.

Last checked: (changes only when the Semaglutide data changes)

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Figures generated from the Dosify Me compound database on 2026-10-15. Informational use only — not medical advice.