Informational use only — not medical advice. For adults 21 and over. Talk to a qualified healthcare professional before making decisions about medications or supplements.

Home › Peptides › Cagrilintide

Cagrilintide

Weight Loss & Metabolic Diabetes

5mg vial + 2mL BAC water = 10 units = 250mcg — Amounts listed in the Dosify Me data: 250mcg-2.4mg, titrated — Frequency: weekly — Best taken: same day each week

Informational only, not medical advice. Consult a licensed healthcare provider before starting or changing any protocol.

Amounts and schedules here are listed from the Dosify Me compound data (sources below). They are not recommendations: Dosify Me does not tell you what dose to take, so follow your prescriber.

Reconstitution

Vial sizes up to 5 mg are mixed to 2.5 mg/mL. Larger vials hold at most 3 mL of water, so they are mixed more concentrated and need fewer units per dose.

Vial	Bacteriostatic water	Concentration
5 mg	2.00 mL	2.5 mg/mL
10 mg^*	3.00 mL	3.33 mg/mL

^* This size is conventionally mixed more concentrated rather than diluted further — fewer units per dose than smaller vials of this peptide.

Dose to syringe units

On a standard 100-unit (1 mL) insulin syringe, for vials mixed to 2.5 mg/mL (sizes marked * are more concentrated and need fewer units):

Dose	Syringe units
250 mcg	10.0 units
600 mcg	24.0 units
1.2 mg	48.0 units
2.4 mg	96.0 units

Amounts listed in the Dosify Me data: 250–2400 mcg. Frequency: weekly. Timing: same day each week, with or without food.

The 5mg reference vial mixes to 2.5mg/mL. Larger vial size options are capped at ~3mL BAC water instead of diluted further, so they come out more concentrated (fewer units per dose) than this reference size.

Reading units for Cagrilintide

Syringe units measure volume, not the amount of Cagrilintide: on a U-100 insulin syringe 100 units is 1 mL.
The vial is labelled in mg while quantities are often written in mcg: 1 mg is 1000 mcg, so a 5 mg vial holds 5000 mcg.
Vials of 10 mg and larger hold at most 3 mL of water, so they are mixed stronger than the smaller sizes and the same quantity reads fewer units.

Check one row of the table above: 250 mcg is 0.25 mg; 0.25 mg ÷ 2.5 mg/mL = 0.1 mL; 0.1 mL × 100 = 10 units.

What it does

An amylin analog that activates amylin and calcitonin receptors in the hindbrain and brainstem — areas that sit outside the blood-brain barrier and directly sense fullness signals from the gut.
Slows gastric emptying by roughly 40-50%, so food sits in the stomach longer and the feeling of fullness after a meal lasts longer.
Suppresses hunger signals and reduces food-reward drive (the pull toward highly palatable food) through brain pathways that are separate from GLP-1 drugs like semaglutide — which is why combining the two produces an additive effect rather than just overlapping ones.
Often studied and taken alongside GLP-1 drugs like semaglutide for exactly that reason.
In clinical trials (as part of CagriSema) for obesity and type 2 diabetes, showing added weight loss on top of semaglutide alone.
Not yet independently FDA-approved — still in late-stage clinical development as of this writing.
As an amylin analog, cagrilintide also suppresses the pancreas's own glucagon release — the opposite direction from drugs that directly activate the glucagon receptor (like retatrutide, mazdutide, or survodutide). Since those drugs activate that receptor themselves rather than depending on the body's own glucagon, this is a theoretical tension rather than a confirmed one, and no published trial has studied cagrilintide combined with any of them.

Why it is listed under Weight Loss & Metabolic, Diabetes

Weight Loss & Metabolic: Reduces appetite as an amylin analog in obesity clinical trials.
Diabetes: Studied (with semaglutide, as CagriSema) for type 2 diabetes in phase 2 trials.

What users report

Anecdotal and early-research reports, kept apart from the evidence above. Not clinically established.

Users report strong, lasting fullness after meals and much less snacking, especially when combined with a GLP-1 drug.
Some report less 'reward' from favourite foods — sweets and rich food simply becoming less interesting.
Reports of smoother, more even appetite control than GLP-1 alone are common and consistent with the trial design, but not established on its own.
As with the GLP-1 class, reduced alcohol interest is sometimes reported and unverified.

Side effects

Nausea in ~20-47% depending on dose, peaking early in each dose step.
Vomiting, diarrhea, constipation.
Usually mild, resolving within 4-8 weeks.

Medication caution

Pramlintide, the FDA-approved amylin analog in this same drug class, carries a boxed warning for severe hypoglycemia when combined with insulin — insulin doses typically need to be reduced when starting an amylin analog. Cagrilintide also slows gastric emptying, which can change the absorption of other oral medications, including thyroid medication. Talk to your prescribing doctor before combining, especially if you use insulin.

Commonly paired with

Semaglutide — Semaglutide suppresses appetite via GLP-1 receptors while cagrilintide works through separate amylin pathways, so combining them (as CagriSema) produces added weight loss rather than just overlapping effects.

Cagrilintide calculator

Different vial or dose? Open the Cagrilintide reconstitution calculator, pre-filled with these numbers.

Frequently asked

How many units is 250 mcg of Cagrilintide?

At 2.5 mg/mL (the standard mix for vials up to 5 mg), 250 mcg of Cagrilintide is 10.0 units on a 100-unit insulin syringe (0.100 mL).

How many units is 600 mcg of Cagrilintide?

At 2.5 mg/mL (the standard mix for vials up to 5 mg), 600 mcg of Cagrilintide is 24.0 units on a 100-unit insulin syringe (0.240 mL).

How many units is 1.2 mg of Cagrilintide?

At 2.5 mg/mL (the standard mix for vials up to 5 mg), 1.2 mg of Cagrilintide is 48.0 units on a 100-unit insulin syringe (0.480 mL).

How much bacteriostatic water do I add to a 5 mg vial of Cagrilintide?

2.00 mL, which gives 2.5 mg/mL. Larger vials hold at most 3 mL of water, so they are mixed more concentrated and need fewer units per dose.

How much bacteriostatic water do I add to a 10 mg vial of Cagrilintide?

3.00 mL, which gives 3.33 mg/mL. This size holds at most 3 mL of water, so it is mixed more concentrated and the same dose is fewer units than from a smaller vial.

How often is Cagrilintide taken?

Weekly. Same day each week, with or without food Typical cycle: Often run continuously; tapering is done under guidance.

Is “cagri” the same as Cagrilintide?

Yes. “cagri” is the short name people use for Cagrilintide in forums and search, and every figure on this page is for that same compound. The units, water and schedule above do not change with the spelling.

Dosify Me does this math for you. Pick the compound, your vial size and dose, and the app draws the exact syringe reading, keeps your schedule and reminders, and logs every dose — privately, on your phone.

Get Dosify Me on Google Play Get Dosify Me on the App Store

Sources

About these figures

Published by San Tan Group, LLC, the company that makes the Dosify Me app. About Dosify Me

Figures come from the Dosify Me compound database for Cagrilintide: concentration is the vial amount ÷ the water volume, and syringe units are the volume in mL × 100 on a U-100 syringe.

Last checked: 2026-10-15 (changes only when the Cagrilintide data changes)

Related pages and guides

Figures generated from the Dosify Me compound database on 2026-10-15. Informational use only — not medical advice.